Stem cells are cells found in most, if not all, multi-cellular
organisms. They are characterized by the ability to renew themselves
through mitotic cell division and differentiating into a diverse range
of specialized cell types. For more information on Stem Cells, please visit http://stemcells.nih.gov/info/basics/defaultpage.asp.
The practical definition of a stem cell is the
functional definition - the ability to regenerate tissue over a lifetime
The term adult stem cell refers to any cell which is
found in a developed organism that has two properties: the ability to
divide and create another cell like itself and also divide and create a
cell more differentiated than itself. Stem cells
obtained from the cord blood at the live birth of an infant are
considered adult stem cells.
Stem cells have the remarkable potential to develop
into many different cell types in the body. It serves as a sort of
repair system for the body, they can theoretically divide without limit
to replenish other cells as long as the person or animal is still
living. When a stem cell divides, each new cell can potentially either
remain a stem cell or become another type of cell with a more
specialized function, such as a muscle cell, a red blood cell, or a
brain cell.
Adult stem cell treatments have been successfully
used for many years to treat leukemia and related bone/blood cancers
through bone marrow transplants. Adult stem cells are also used in
veterinary medicine to treat tendon and ligament injuries in horses.[23] The use of adult stem cells in research and therapy is not as
controversial as embryonic stem cells, because the production of adult
stem cells does not require the destruction of an embryo. Additionally,
because in some instances adult stem cells can be obtained from the
intended recipient, (an autograft) the risk of rejection is essentially non-existent in
these situations. Consequently, more US government funding is being
provided for adult stem cell research.
Medical researchers believe that stem cell therapy
has the potential to dramatically change the treatment of human disease.
A number of adult stem cell therapies already exist, particularly bone
marrow transplants that are used to treat leukemia. In the future,
medical researchers anticipate being able to use technologies derived
from stem cell research to treat a wider variety of diseases including
cancer, Parkinson's disease, spinal cord injuries, Amyotrophic lateral
sclerosis, multiple sclerosis, and muscle damage, amongst a number of
other impairments and conditions. However, there still exists a
great deal of social and scientific uncertainty surrounding stem cell
research, which could possibly be overcome through public debate and
future research, and further education of the public.
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